What does diabetic dermopathy look like

what does diabetic dermopathy look like

Description Summary: Glucagonoma and pancreatic serous oligocystic adenoma SOA are rare neuroendocrine and exocrine tumors of the pancreas, respectively. The coexistence of glucagonoma syndrome GS and SOA is a rare clinical condition and has not yet been reported. Additionally, necrolytic migratory erythema NMEa hallmark clinical sign of GS, is often misdiagnosed as other skin lesions by clinicians due to their lack of related knowledge, which delays diagnosis of GS and thus exacerbates the prognosis.

what does diabetic dermopathy look like

A year-old male patient was admitted to our department because he presented with diabetes mellitus and a recurrent ulcerated skin rash. Prior to the accurate diagnosis, the skin manifestation was considered to be diabetic dermopathy.

The patient's fasting serum glucagon level was up to A biopsy of the pancreatic tumor revealed a pancreatic neuroendocrine tumor, and immunoperoxidase staining revealed glucagon-positive cells. In addition, the histological examination of the pancreatic cystic lesions showed typical features of SOA.

The patient received a pancreaticoduodenal resection and radiofrequency ablation for the hepatic nodular lesion.

what does diabetic dermopathy look like

One week after surgery, the glucagon concentration decreased to near normal levels. The cutaneous lesions spontaneously resolved within 4 weeks after surgery. Because almost all glucagonomas are malignant or have malignant potential, their early recognition and correct diagnosis are very important for a better prognosis, especially in cases with NME as the only manifestation during the development of glucagonomas.

Irodalmi cukorbetegség Panzió és 2-es típusú cukorbetegség Diabetes can cause changes in the skin of your foot. At times your foot may become very dry. The skin may peel and crack. Diabetes can cause the skin of your foot to become very dry, which causes peeling and cracking. This happens because the nerves that control the oil and moisture in your foot no longer work.

It is therefore imperative that clinicians recognize NME early to make an accurate diagnosis.